Methods for diagnosis of low grade astrocytoma

G - Physics – 01 – N

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G01N 33/574 (2006.01) C07K 16/30 (2006.01) C12Q 1/68 (2006.01) G01N 33/564 (2006.01)

Patent

CA 2407760

A method for identifying low grade astrocytoma cells in a sample is provided, wherein the method distinguishes between low grade astrocytoma cells and normal astrocytes, thus permitting early diagnosis of astrocytoma. The method uses antibody directed against J1-31 to test astrocytes in the sample for the presence or absence of J1-31 polypeptide, the low grade astrocytoma cells being characterized by the absence of J1-31 while normal astrocytes are characterized by the presence of J1-31.

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