G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01)
Patent
CA 2546461
The inventors have discovered a collection of proteinaceous biomarkers ("AD biomarkers) which can be measured in peripheral biological fluid samples to aid in the diagnosis of neurodegenerative disorders, particularly Alzheimer's disease and mild cognitive impairment (MCI). The invention further provides methods of identifying candidate agents for the treatment of Alzheimer's disease by testing prospective agents for activity in modulating AD biomarker levels.
L'invention concerne un recueil de biomarqueurs protéiques (biomarqueurs AD) pouvant être mesurés dans des échantillons fluidiques biologiques périphériques, pour aider à diagnostiquer des troubles neurodégénératifs, en particulier, la maladie d'Alzheimer, et une déficience cognitive légère (MCI). L'invention concerne également des méthodes d'identification d'agents candidats pour le traitement de la maladie d'Alzheimer en testant des agents susceptibles de présenter une activité dans la modulation des niveaux de biomarqueurs AD.
Ray Sandip
Wyss-Coray Anton
Borden Ladner Gervais Llp
Satoris Inc.
The Board Of Trustees Of The Leland Standford Junior University
The U.s. Government Represented By The Department Of Veterans Af
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