Methods for display of heterodimeric proteins on filamentous...

Details Methods for display of heterodimeric proteins on filamentous... Methods for display of heterodimeric proteins on filamentous...

C - Chemistry, Metallurgy

12

N

C12N 15/70 (2006.01) C07K 16/00 (2006.01) C07K 19/00 (2006.01) C12N 5/12 (2006.01) C12N 7/01 (2006.01) C12N 15/00 (2006.01) C12N 15/10 (2006.01) C12N 15/13 (2006.01) C12N 15/63 (2006.01) C40B 40/02 (2006.01)

Patent

CA 2374505

The invention describes the display of exogenous polypeptides on filamentous phage using a fusion between the exogenous polypeptide and phage pVII or pIX proteins. In particular, phage particles and phagemid vectors are described for expression and display of heterodimeric proteins such as antibody Fv heterodimers in combinatorial libraries, and uses thereof.

L'invention concerne l'affichage de polypeptides exogènes sur un phage filamenteux au moyen d'une fusion entre le polypeptide exogène et les protéines pVII ou pIX phage. L'invention concerne plus particulièrement les particules de phage et les vecteurs phagémides servant à l'expression et à l'affichage de protéines hétérodimères telles que des hétérodimères d'un anticorps Fv dans des banques combinatoires. L'invention concerne également leurs utilisations.

Affiliated with

Also associated with

Rating

Methods for display of heterodimeric proteins on filamentous... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for display of heterodimeric proteins on filamentous..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for display of heterodimeric proteins on filamentous... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1771525