Methods for embolizing aneurysmal sites with a high...

A - Human Necessities – 61 – L

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A61L 17/10 (2006.01) A61B 17/12 (2006.01) A61K 31/74 (2006.01) A61L 24/00 (2006.01) A61L 31/14 (2006.01) A61L 31/18 (2006.01)

Patent

CA 2469734

Novel methods for embolizing blood vessels which are particularly suited for treating aneurysms are provided. The presently disclosed methods provide for the embolization of aneurysms wherein occlusion of the neck of the aneurysm during embolization by a flow arresting device such as balloon is not required. In one embodiment, the compositions employed in the methods of this invention comprise a biocompatible polymer, a biocompatible solvent and a biocompatible contrast agent wherein the viscosity of this composition is at least about 1000 centistokes at 40 C and, preferably, at least about 2500 centistokes at 40 C.

Cette invention a trait à de nouvelles techniques d'embolisation de vaisseaux sanguins, se révélant des plus utiles en matière de traitement d'anévrismes. Les techniques selon l'invention permettent de procéder à une embolisation d'anévrismes au cours de laquelle une occlusion du col de l'anévrisme par un dispositif faisant cesser tout débit sanguin n'est pas nécessaire. Dans un mode de réalisation, les compositions utilisées contiennent un polymère, un solvant et un agent de contraste biocompatibles. La viscosité de cette composition est au moins de 1000 centistokes à 40 ·C et, de préférence, d'au moins 2500 centistokes à 40 ·C.

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