Methods for entrapment of bioactive agent in a liposome or...

Details Methods for entrapment of bioactive agent in a liposome or... Methods for entrapment of bioactive agent in a liposome or...

A - Human Necessities

61

K

A61K 9/127 (2006.01) A61K 9/133 (2006.01)

Patent

CA 2477982

A method of preparing a liposomal bioactive agent comprising infusing an lipid- ethanol mixture with an aqueous or ethanolic solution of the bioactive agent at a temperature below the phase transition of at least one of the lipid components of the lipid and compositions produced by the method of the invention.

L'invention concerne un procédé de préparation d'un agent bioactif liposomique consistant en l'infusion d'un mélange de lipides-éthanol avec une solution aqueuse ou éthanolique de l'agent bioactif, à une température inférieure à la température de transition de phase d'au moins un des constituants lipidiques du lipide, ainsi que des compositions produites par le procédé de l'invention.

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