Methods for ex vivo therapy using peptide-loaded antigen...

Details Methods for ex vivo therapy using peptide-loaded antigen... Methods for ex vivo therapy using peptide-loaded antigen...

A - Human Necessities

61

K

A61K 35/14 (2006.01) A61K 38/00 (2006.01) C12N 5/08 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2168950

Methods for activating cytotoxic T lymphocytes (CTL) in vitro are presented in conjunction with methods for using the activated CTL for therapy in vivo. Additionally, a method for killing specific CTL in vivo is presented using antigen presenting cells which were modified in vitro.

L'invention concerne des procédés qui permettent d'activer des CTL (lymphocytes T cytotoxiques) in vitro, en conjonction avec des procédés qui permettent d'utiliser ces CTL activés en thérapie in vivo. En outre, l'invention concerne un procédé permettant de tuer in vivo des CTL spécifiques à l'aide de cellules présentatrices d'antigènes modifiées in vitro.

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