A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 38/09 (2006.01) A61P 15/08 (2006.01)
Patent
CA 2304662
The present invention relates to a polymer-based sustained release device, and methods of forming and using the device for the sustained release of an active agent. The improved method of the invention for forming a polymer-based sustained release device comprises forming a polymer/active agent solution by mixing a polymer, a continuous phase, and an active agent. The continuous phase can comprise one or more polymer solvents, a polymer solvent/polymer non-solvent mixture, or a polymer solvent/active agent non-solvent mixture. When the continuous phase comprises a polymer solvent/active agent non- solvent, the active agent can also be present as a microparticulate rather than in solution. The continuous phase is then removed from the polymer/active agent solution, thereby forming a solid polymer/active agent matrix.
La présente invention concerne un dispositif de libération prolongée à base de polymère et des procédés de fabrication et d'utilisation dudit dispositif pour la libération prolongée d'un principe actif. Le procédé amélioré de la présente invention, qui permet de former un dispositif de libération prolongée à base de polymère, consiste à former une solution de polymère/principe actif en mélangeant un polymère, une phase continue et un principe actif. La phase continue peut comprendre un ou plusieurs solvants polymériques, un mélange solvant polymérique/non solvant polymérique, ou un mélange solvant polymérique/non solvant de principe actif. Lorsque la phase continue comprend un solvant polymérique/non solvant de principe actif, le principe actif peut également être présent sous forme de microparticule plutôt que sous forme de solution. On crée alors une matrice solide polymère/principe actif en retirant la phase continue de la solution polymère/principe actif.
Burke Paul A.
Herberger John D.
Herbert Paul F.
Tracy Mark A.
Alkermes Controlled Therapeutics Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Methods for fabricating polymer-based controlled release... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for fabricating polymer-based controlled release..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for fabricating polymer-based controlled release... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1973276