Methods for fine powder formation

Details Methods for fine powder formation Methods for fine powder formation

B - Operations, Transporting

01

J

B01J 2/04 (2006.01) A61J 3/02 (2006.01) A61K 9/14 (2006.01) A61K 38/28 (2006.01) B01D 9/04 (2006.01)

Patent

CA 2575973

Improved methods for forming fine particles of a material have been developed, wherein the method steps include dissolving the material in a solvent to form a dilute solution, immobilizing the dilution solution, and then removing the solvent to yield particles of the material. Methods of immobilizing the dilute solution include freezing, gelation, and chelation. In a preferred embodiment, the immobilized solvent is removed by lyophilization, i.e. reducing the ambient pressure while avoiding application of sufficient heat to power a phase transition. Essentially any material and solvent for the material can be used in the methods described herein. Proteins and peptides in an aqueous solvent are the preferred systems.

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