A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/12 (2006.01) A61K 9/127 (2006.01) A61K 38/20 (2006.01) A61P 31/12 (2006.01) A61K 39/385 (2006.01)
Patent
CA 2692546
The present invention is in the fields of drug delivery, and specifically, cationic liposome-based vaccines. In embodiments, this invention provides methods of making ligand-targeted (e.g., antibody-or antibody fragment-targeted) liposomes useful for the delivery of molecules to induce immune responses against viral antigens or to treat or prevent viral diseases. The specificity of the delivery system is derived from the targeting ligands.
L'invention concerne l'administration de médicaments et, spécifiquement, de vaccins à base de liposome cationique. Dans des modes de réalisation, l'invention fournit des procédés de fabrication ciblant des ligands de liposomes (par exemple des anticorps ou des fragments d'anticorps) servant à administrer des molécules pour induire des réponses immunitaires contre des antigènes viraux ou pour traiter ou prévenir des maladies virales. La spécificité du système d'administration vient des ligands de ciblage.
Chang Esther H.
Pirollo Kathleen F.
Georgetown University
Osler Hoskin & Harcourt Llp
LandOfFree
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