Methods for generating insulin-producing cells

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/071 (2010.01) C12N 5/0775 (2010.01) A61K 35/39 (2006.01) A61P 3/10 (2006.01) C12N 5/02 (2006.01)

Patent

CA 2581424

This invention relates to methods for generating insulin-producing cells. In particular, the present invention relates to methods for generating insulin- producing cells or precursors thereof in vitro or in vivo by employing mesenchymal stem cells an pancreatic cells. Insulin-producing cells or precursors thereof created in accordance with the present methods, as well as the use of these cells in the treatment of diabetes, are also provided.

L'invention concerne des procédés d'obtention de cellules produisant de l'insuline. L'invention concerne en particulier des procédés d'obtention de cellules produisant de l'insuline ou des précurseurs de celles-ci in vitro ou in vivo au moyen de cellules souches mésenchymateuses et de cellules pancréatiques. L'invention concerne également des cellules produisant de l'insuline ou des précurseurs de celles-ci obtenus selon lesdits procédés, ainsi que leur utilisation dans le traitement du diabète.

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