Methods for generating monovalent igg

Details Methods for generating monovalent igg Methods for generating monovalent igg

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2626013

The present invention relates to monovalent antibody, methods of making thereof and therapeutic uses thereof. In particular, the present invention provides a heterodimeric polypeptide comprising an immunoglobulin heavy chain and a fusion protein comprising an immunoglobulin light chain and an Fc molecule.

La présente invention a trait à un anticorps monovalent, à ses procédés de fabrication et à ses utilisations thérapeutiques. En particulier, la présente invention a trait à un polypeptide hétérodimérique comportant une chaîne lourde d'immunoglobuline et une protéine hybride comportant une chaîne légère d'immunoglobuline et une molécule Fc.

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