A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 35/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/00 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2453531
Described are compositions and methods relating to gene therapy, particularly as applied to hematopoietic progenitor (HP) cells, to transduced cells and methods of obtaining them, and to methods of using them to provide prolonged engraftment of modified hematopoietic cells in human subjects. The invention particularly relates to ex vivo gene therapy of HP cells for treatment or prevention of HIV infection.
L'invention porte sur des compositions et sur des procédés relatifs à la thérapie génique et s'appliquant notamment aux cellules progénitrices hématopoïétiques, à des cellules de transduction et à leur procédé de production et à des procédés utilisant ces cellules pour obtenir une prise de greffe prolongée des cellules hématopoïétiques modifiées chez l'homme. L'invention porte notamment sur la thérapie génique ex vivo des cellules hématopoïétiques s'utilisant dans le traitement ou la prévention de l'infection par le VIH.
Amado Rafael
Fanning Greg
Gerlach Wayne
Macpherson Janet
Sun Lun-Quan
Amado Rafael
Fanning Greg
Gerlach Wayne
Johnson & Johnson Research Pty Limited
Macpherson Janet
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