Methods for heterologous expression of secondary metabolites

Details Methods for heterologous expression of secondary metabolites Methods for heterologous expression of secondary metabolites

C - Chemistry, Metallurgy

12

N

C12N 15/63 (2006.01) C12N 1/21 (2006.01)

Patent

CA 2584777

The invention provides a method for the heterologous expression of a secondary metabolite encoded by a biosynthetic pathway. Also provided is a method for introducing a large sized DNA molecule into the chromosome of a heterologous host using a transposable element. Novel myxochromide S derivatives are also provided.

L'invention concerne une méthode d'expression hétérologue d'un métabolite secondaire codé par une voie biosynthétique. L'invention concerne également une méthode d'introduction d'une molécule d'ADN de grande taille dans le chromosome d'un hôte hétérologue à l'aide d'un élément transposable. L'invention concerne en outre de nouveaux dérivés de myxochromides S.

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