G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/574 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2723648
The invention relates to methods for identifying compounds and compositions that target cancer stem cells. In some aspects, the invention relates to treatment methods that use compounds and compositions that specifically target cancer stem cells for inhibiting the growth and/or survival of cancer stem cells in a subject in need thereof. Other aspects of the invention relate to the use of cancer stem cell biomarkers in the selection of a treatment for inhibiting the growth and/or survival of cancer stem cells in a subject in need thereof.
La présente invention concerne des procédés destinés à identifier des composés et des compositions qui ciblent les cellules souches cancéreuses. Selon certains aspects, la présente invention concerne des procédés de traitement qui utilisent des composés et des compositions ciblant spécifiquement des cellules souches cancéreuses afin den inhiber la croissance et/ou la survie chez un sujet nécessitant ce traitement. Dautres aspects de la présente invention concernent lutilisation de biomarqueurs de cellules souches cancéreuses pour choisir un traitement visant à inhiber la croissance et/ou la survie de cellules souches cancéreuses chez un sujet nécessitant ce traitement.
Gupta Piyush
Lander Eric S.
Liao Mai-Jing
Mani Sendurai
Onder Tamer T.
Massachusetts Institute Of Technology
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Whitehead Institute For Biomedical Research
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