Methods for identifying agents that cause a lethal...

Details Methods for identifying agents that cause a lethal... Methods for identifying agents that cause a lethal...

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/554 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2400328

The present invention is directed to methods for performing negative selection assays leading to the identification of cytostatic or cytotoxic agents that cause a lethal phenotype. The invention is useful also for evaluation of conditional cytotoxicity and cell-specific cytotoxicity.

L'invention concerne des procédés d'exécution de dosages de sélection négative permettant d'identifier des agents cytostatiques ou cytotoxiques provoquant un phénotype létal. Cette invention est également utile dans l'évaluation d'une éventuelle cytotoxicité et d'une cytotoxicité spécifique de cellules.

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