Methods for identifying antimicrobial compounds

Details Methods for identifying antimicrobial compounds Methods for identifying antimicrobial compounds

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A23J 3/34 (2006.01) G01N 33/569 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2497411

The present invention relates to arrays for bacterial gene expression profiling in response to treatment with antimicrobial compounds. Bacterial nucleic acid molecules are used as the hybridizable elements in various applications, such as arrays for gene expression profiling and for determining a mode of action for an antimicrobial compound. The present invention also relates to nucleic acid sequences which can be developed as targets for drug screening.

La présente invention concerne des jeux ordonnés d'échantillons permettant de déterminer des profils d'expression génétique bactérienne en réponse au traitement à l'aide de composés antimicrobiens. Des molécules d'acide nucléique bactérien sont utilisées en tant qu'éléments pouvant être hybridés dans diverses applications, ainsi qu'en tant que jeux ordonnés d'échantillons permettant de déterminer des profils d'expression génétique et permettant de déterminer un mode d'action d'un composé antimicrobien. La présente invention concerne également des séquences d'acides nucléiques qui peuvent être développées en tant que cibles pour le criblage de médicaments.

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