Methods for identifying antimicrobial peptides that interact...

Details Methods for identifying antimicrobial peptides that interact... Methods for identifying antimicrobial peptides that interact...

C - Chemistry, Metallurgy

12

Q

C12Q 1/18 (2006.01) A61K 38/43 (2006.01) C07K 14/245 (2006.01) C07K 14/31 (2006.01) C07K 16/40 (2006.01) C12N 9/02 (2006.01) C12N 15/53 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01) G01N 33/68 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2319115

Methods and mutants for identifying an antimicrobial compound which interacts with an ER polypeptide are disclosed. In particular, the method pertains to the screens for identifying an antimicrobial compound using FabI or InhA mutant cells or polypeptides.

Procédés et mutants servant à identifier un composé antimicrobien exerçant une interaction avec un polypeptide ER. Ce procédé consiste, en particulier, à identifier par criblage un composé antimicrobien au moyen de cellules mutantes ou de polypeptides FabI ou InhA.

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