Methods for identifying compounds for inhibition of...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/16 (2006.01) A61K 31/00 (2006.01) A61K 31/165 (2006.01) A61K 31/192 (2006.01) A61K 31/365 (2006.01) A61K 31/4192 (2006.01) C12Q 1/18 (2006.01) C12Q 1/26 (2006.01) C12Q 1/44 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2284853

Pharmaceutical compositions for the treatment of neoplasia can be selected by identifying compounds that inhibit cGMP phosphodiesterase and increase PKG activity in neoplastic cells.

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