C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 31/7088 (2006.01) A61K 38/05 (2006.01) A61K 38/22 (2006.01) A61K 38/25 (2006.01) A61K 38/26 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) G01N 33/50 (2006.01) G01N 33/566 (2006.01) G01N 33/567 (2006.01)
Patent
CA 2426779
Screening methods for identifying compounds that regulate skeletal muscle atrophy or hypertrophy, regulate the activity or expression of the vasoactive intestinal peptide receptors (VPAC) or regulate expression of vasoactive intestinal peptide (VIP) or VIP analogs are provided. Methods for prophylactic or therapeutic treatment of skeletal muscle atrophy utilizing VPAC as the target for intervention are described.
L'invention porte sur des procédés de criblage destinés à identifier des composés qui régulent l'atrophie ou l'hypertrophie musculaire du squelette, l'activité ou l'expression des récepteurs peptidiques intestinaux vasoactifs ou l'expression des peptides intestinaux vasoactifs ou leurs analogues. L'invention porte également sur des procédés de traitement prophylactique ou thérapeutique de l'atrophie musculaire du squelette au moyen des récepteurs précités utilisés comme cible d'intervention.
Isfort Robert Joseph
Sheldon Russell James
Ledgley Law
The Procter & Gamble Company
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