Methods for identifying compounds that bind to a target

Details Methods for identifying compounds that bind to a target Methods for identifying compounds that bind to a target

C - Chemistry, Metallurgy

07

K

C07K 4/00 (2006.01) C07K 1/04 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/554 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2238995

Methods for identifying a compound that binds to a target are described. In general, the methods involve forming a first library comprising a multiplicity of peptides, identifying one or more peptides that bind to the target and determining a peptide motif therefrom, forming a second library comprising a multiplicity of compounds designed based on the peptide motif, selecting from the second library at least one compound that binds to the target, and determining the structure or structures of the at least one compound that binds to the target. Libraries of compounds based on a peptide motif and compounds identified by the methods of the invention are also disclosed.

Procédés d'identification d'un composé qui se lie à une cible. D'une manière générale, ces procédés impliquent la réalisation d'une première banque comprenant plusieurs peptides, l'identification d'un ou plusieurs peptides qui se lient à la cible et la détermination en conséquence d'un motif de peptide, la constitution d'une deuxième banque comprenant plusieurs composés conçus sur la base du motif de peptide, la sélection, dans cette deuxième banque, d'au moins un composé qui se lie à la cible et la détermination de la ou des structures de ce ou de ces composés qui se lient à la cible. L'invention porte également sur les banques de composés basés sur un motif de peptide et sur les composés identifiés grâce à ces méthodes.

Affiliated with

Also associated with

Rating

Methods for identifying compounds that bind to a target does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for identifying compounds that bind to a target, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for identifying compounds that bind to a target will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1506974