C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/48 (2006.01) C12N 9/10 (2006.01)
Patent
CA 2362985
The present invention relates to methods for identifying compounds useful as inhibitors of farnesyl diphosphate synthase. More particularly, the compounds so identified are useful for inhibiting bone resorption. The present invention also relates to methods for inhibiting bone resorption in a mammal comprising administering to a mammal in need thereof a therapeutically effective amount of a farnesyl diphosphate synthase inhibitor.
La présente invention a trait à des procédés d'identification de composés utiles comme inhibiteurs de farnésyle diphosphate synthase. Plus particulièrement, les composés ainsi identifiés servent à inhiber la résorption osseuse. La présente invention a également trait à des procédés visant à inhiber la résorption osseuse chez un mammifère, qui comportent l'administration d'une quantité thérapeutiquement efficace d'un inhibiteur de farnésyle diphosphate synthase à un mammifère nécessitant un tel traitement.
Bergstrom James D.
Reszka Alfred A.
Rodan Gideon A.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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