Methods for identifying genes essential to the growth of an...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2270153

The present invention provides methods for identifying genes essential to the growth of an organism using a grid prepared from a genomic library of a selected organism. Genes identified as essential by this method and proteins encoded thereby are also provided. In addition, methods of using these genes and proteins encoded thereby are disclosed.

La présente invention concerne des procédés d'identification de gènes indispensables à la croissance d'un organisme, lesquels procédés consistent à utiliser une grille préparée à partir d'une banque génomique d'un organisme choisi. L'invention concerne également des gènes identifiés par ce procédé comme étant indispensables ainsi que des protéines codées par ceux-ci. En outre, l'invention concerne des procédés d'utilisation de ces gènes et des protéines codées par ceux-ci.

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