Methods for identifying glucose uptake modulators

Details Methods for identifying glucose uptake modulators Methods for identifying glucose uptake modulators

G - Physics

01

N

G01N 33/567 (2006.01) A61K 38/28 (2006.01) A61K 45/00 (2006.01) A61P 3/10 (2006.01) C12Q 1/02 (2006.01) C12Q 1/54 (2006.01) G01N 33/66 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2485220

The present invention relates to methods for identifying agents modulating store-operated Ca2+ entry and thereby modulating glucose uptake in mammalian cells. Such compounds may be useful for the treatment of diseases connected with reduced glucose uptake, such as type 2 diabetes.

L'invention concerne des procédés permettant l'identification d'agents modulant l'entrée de Ca?2+¿ de mise en réserve et, de ce fait, modulant le stockage du glucose dans des cellules de mammifères. De tels composés peuvent être utilisés pour le traitement de maladies liées à un captage de glucose réduit, telles que diabètes de type II.

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