C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/04 (2006.01) C12Q 1/02 (2006.01) C40B 30/00 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2609541
The present invention provides methods for the identification of novel ligands to pluripotent stem cells such as human embryonic stem cells, human embryo- derived cells, and from cells differentiated from such cells, and the use of such ligands in identifying differentiation conditions, purifying cells, and for eliminating such cells from mixtures of varied cell types. The invention also provides methods for the identification of target progenitor cells and cells identified thereby.
La présente invention concerne des méthodes destinées à l'identification de nouveaux ligands pour des cellules souches pluripotentes, telles que des cellules souches embryonnaires humaines, des cellules dérivées d'embryons humains, et des cellules différenciées à partir de ces cellules, ainsi que l'utilisation de ces ligands pour l'identification de conditions de différenciation, la purification de cellules et pour l'élimination de ces cellules de mélanges contenant divers types de cellules. L'invention concerne également des méthodes destinées à l'identification de cellules souches cibles et des cellules ainsi identifiées.
Chapman Karen B.
Larocca David
West Michael D.
Advanced Cell Technology Inc.
Gowling Lafleur Henderson Llp
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