Methods for identifying merle mutations in the silv gene

Details Methods for identifying merle mutations in the silv gene Methods for identifying merle mutations in the silv gene

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2619841

Animals with mutations in SILV present with the merle coat color pattern phenotype. Methods for the identification of animals that harbor a mutation in the SILV gene are described. Mutations in the SILV gene can be identified from any biological sample such as a cell or tissue that contains genomic DNA. A microsatellite marker identified using linkage disequilibrium mapping that segregates with merle is also described.

L'invention concerne les animaux présentant des mutations dans le SILV présent avec le phénotype du motif de couleur de revêtement merle. Elle concerne également des procédés pour identifier les animaux qui présentent une mutation dans le gène SILV. Ces mutations peuvent être identifiées à partir de n'importe quel échantillon biologique, à savoir une cellule ou un tissu contenant un ADN génomique. L'invention concerne aussi un marqueur microsatellite identifié au moyen du relevé de déséquilibre de liaison qui se sépare du merle.

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