Methods for identifying, purifying and enriching immature or...

Details Methods for identifying, purifying and enriching immature or... Methods for identifying, purifying and enriching immature or...

G - Physics

01

N

G01N 33/574 (2006.01)

Patent

CA 2706293

The present invention is related to methods for the preparation of cell compositions, isolated compositions obtainable therefrom, related isolated cell compositions, kits and use thereof. More specifically, the present invention provides a method for identifying, purifying and enriching immature or stem cancer-initiating cells in a 5 sample. The cell compositions, related methods and uses according to the present invention are useful in the treatment of cancers and/or the detection of enriching immature or stem cancer-initiating cells, notably cancers of the central and peripheral nervous system, metastasis to the brain.

La présente invention porte sur des procédés pour la préparation de compositions cellulaires, de compositions isolées pouvant être obtenues à partir de celles-ci, de compositions cellulaires isolées apparentées, sur des coffrets et leur utilisation. Plus spécifiquement, la présente invention porte sur un procédé pour identifier, purifier et enrichir des cellules initiant un cancer immatures ou souches dans un échantillon. Les compositions cellulaires, les procédés apparentés et les utilisations selon la présente invention sont utiles dans le traitement de cancers et/ou la détection de cellules initiant un cancer immatures ou souches enrichies, notamment des cancers du système nerveux central et périphérique, une métastase au cerveau.

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