Methods for identifying risk of breast cancer and treatment...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/48 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2569100

Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.

L'invention concerne des procédés d'identification du risque de cancer du sein chez un sujet et/ou un sujet à risque, des réactifs et des ensembles de mise en oeuvre des procédés selon l'invention, des procédés d'identification d'agents thérapeutiques candidats destinés au traitement du cancer du sein, et des procédés thérapeutiques destinés au traitement du cancer du sein chez un sujet. Les procédés selon l'invention reposent sur une analyse de variations polymorphiques dans des séquences nucléotidiques du génome humain.

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