Methods for immuno-detection of epitopes on molecules and...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) A61K 38/04 (2006.01) A61K 38/16 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01) G01N 33/58 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2439235

Methods, systems and kits are provided for detecting molecules expressing a selected epitope in a sample through use of an epitope detector containing a single chain Fv for the selected epitope or a constrained epitope specific CDR, CDR mimetic or engineered CDR structure attached to an oligonucleotide.

La présente invention concerne des méthodes, des systèmes et des trousses qui permettent de détecter des molécules exprimant un épitope sélectionné, dans un échantillon, à l'aide d'un détecteur d'épitope contenant une chaîne unique Fv pour l'épitope sélectionné ou une structure CDR fabriquée ou un mimétique CDR ou un CDR spécifique contre un épitope restreint, qui est attaché à un oligonucléotide.

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