Methods for improving bioavailability of a renin inhibitor

Details Methods for improving bioavailability of a renin inhibitor Methods for improving bioavailability of a renin inhibitor

A - Human Necessities

61

K

A61K 31/165 (2006.01) A61K 45/06 (2006.01) A61P 9/00 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2670160

The present invention provides a method for improving the bioavailability of a renin inhibitor, preferably, of a .delta.-amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid derivative, which method comprises co-administering to a mammal, especially a human, in need of such treatment, a combination of a renin inhibitor, or a pharmaceutically acceptable salt thereof, and an MDR1 inhibitor selected from a non-pharmacologically active compound.

La présente invention concerne un procédé destiné à améliorer la biodisponibilité d'un inhibiteur de la rénine, de préférence, d'un dérivé de l'acide .delta.-amino-.gamma.-hydroxy-.omega.-aryl-alkanoïque, lequel procédé comprend la coadministration à un mammifère, notamment un être humain, nécessitant un tel traitement, d'une combinaison d'un inhibiteur de la rénine, ou d'un sel pharmaceutiquement acceptable de celui-ci, et d'un inhibiteur de MDR1 choisi parmi un composé non-pharmacologiquement actif.

Affiliated with

Also associated with

Rating

Methods for improving bioavailability of a renin inhibitor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for improving bioavailability of a renin inhibitor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for improving bioavailability of a renin inhibitor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1524779