A - Human Necessities – 01 – N
Patent
A - Human Necessities
01
N
A01N 43/04 (2006.01) A61K 31/70 (2006.01) A61K 39/00 (2006.01) A61K 39/21 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01) C07H 21/04 (2006.01) C12N 5/00 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)
Patent
CA 2404041
The invention provides methods for T helper-independent activation of an antigen-specific cytotoxic T lymphocyte response in an individual. The methods generally involve administering to an individual an immunostimulatory nucleic acid molecule in an amount effective to increase an antigen-specific CTL response in the individual. The invention further provides methods for increasing chemokine secretion, which can block HIV infection.
L'invention concerne des procédés d'activation indépendante de T auxiliaires d'une réaction de lymphocytes T cytotoxiques à spécificité antigénique chez un individu. Ces procédés consistent d'ordinaire à administrer à un individu une molécule d'acide nucléique immunostimulateur en dose efficace de façon à augmenter une réaction de lymphocytes T cytotoxiques à spécificité antigénique chez cet individu. L'invention concerne en outre des procédés destinés à augmenter la sécrétion de la chimiokine capable de bloquer l'infection du VIH.
Cho Hearn Jay
Horner Anthony A.
Raz Eyal
Richman Douglas D.
Department Of Veterans Affairs
Fetherstonhaugh & Co.
The Regents Of The University Of California
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