Methods for inhibiting bone loss

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/29 (2006.01) A61K 31/47 (2006.01) A61K 31/473 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/66 (2006.01)

Patent

CA 2220034

The present invention provides methods of inhibiting bone loss in mammals via the administration to a mammal in need of such treatment an effective amount of a compound from a series of benzoquinolin-3-ones. Such compounds also are sequentially or concurrently coadministered with a bone antiresorptive agent or a bone anabolic agent.

La présente invention concerne des procédés permettant d'empêcher les pertes osseuses chez les mammifères, ces procédés consistant à administrer à un mammifère justiciable d'un tel traitement, une quantité efficace d'un composé provenant d'une série de benzoquinoline-3-ones. On administre également ces composés conjointement à un agent bloquant la résorption des os ou à un agent anabolisant, de façon séquentielle ou concomitante.

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