Methods for inhibiting ldl oxidation and atherosclerosis

Details Methods for inhibiting ldl oxidation and atherosclerosis Methods for inhibiting ldl oxidation and atherosclerosis

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 31/40 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2138508

Methods of inhibiting LDL oxidation, atherosclerosis, advanced glycosylation end products, and superoxide anions and other reactive oxygen intermediates, comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula (I) Image wherein R1 and R3 are independently hydrogen, -CH3, Image , or Image , wherein Ar is optionally substituted phenyl; R2 is Image Image Image , , or and pharmaceutically acceptable salts and solvates thereof.

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