Methods for inhibiting or suppressing stenosis of...

A - Human Necessities – 61 – B

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A61B 19/00 (2006.01) A61N 5/06 (2006.01) A61B 17/22 (2006.01) A61B 18/24 (2006.01)

Patent

CA 2466833

A method for inhibiting or suppressing stenosis associated with an arteriovenous access. A dosage of photosensitive compound is introduced into the artery (14) or vein (12). An anastomotic area (16) of the artery (14) or vein (12) is then exposed to a source of light having a wavelength suitable for photoactivating the photosensitive compound for a period of time sufficient to provide a therapeutic effect. A method is also described for the delivery of drugs into the anastomotic site of an AV access to inhibit the formation of stenotic lesions at those sites.

Cette invention concerne un procédé permettant d'inhiber ou d'éliminer une sténose associée à un accès artérioveineux. Une dose d'un composé photosensible est introduite dans l'artère ou la veine. Une zone anastomotique de l'artère ou de la veine est ensuite exposée à une source de lumière dont la longueur d'onde permet de photoactiver le composé photosensible pendant une durée suffisante pour qu'un effet thérapeutique soit produit. Cette invention concerne également une méthode d'administration de médicaments dans le site anastomotique d'un accès artérioveineux afin d'inhiber la formation de lésions sténotiques au niveau de ces sites.

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