A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 45/08 (2006.01) A61K 35/28 (2006.01) A61K 35/32 (2006.01) A61K 39/395 (2006.01) A61L 27/00 (2006.01) A61L 27/36 (2006.01) A61L 27/38 (2006.01) A61P 37/06 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2303008
The present invention provides a method for inhibiting rejection of a transplanted tissue without the use of lethal irradiation. This method comprises grafting bone into a recipient, wherein the bone comprises stromal cells and marrow cells, to induce immunological tolerance of the transplanted tissue by the recipient, thereby inhibiting rejection of the transplanted tissue.
L'invention concerne un procédé permettant d'inhiber le rejet de greffe de tissu sans recourir à une irradiation létale. Le procédé consiste à effectuer une greffe osseuse sur un receveur, l'os comprenant des cellules du stroma et des cellules médullaires, de manière à induire chez ce receveur une tolérance immunitaire, et donc à inhiber le rejet de greffe de tissu.
Alexander Diane Z.
Larsen Christian P.
Pearson Thomas C.
Emory University
Oyen Wiggs Green & Mutala Llp
LandOfFree
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