A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/70 (2006.01) C07H 21/00 (2006.01) C07H 21/02 (2006.01) C12N 15/11 (2006.01)
Patent
CA 2396240
The present invention relates to a novel method for inhibiting the growth, elaboration and/or replication of HIV in human patients and to the prevention and treatment of human acquired immunodefiiciency syndrome (AIDS) and other diseases caused by retroviral infection. In preferred aspects, the present invention provides a method for the use of a novel class of oligodeoxynucleotides consisting of 4-thio-2'-deoxyuridylate units for the prevention and treatment of both wild-type and drug-resistant Human Immunodeficiency Virus 1 (HIV), the causative pathogen of AIDS.
La présente invention concerne une nouvelle méthode destinée à l'inhibition de la croissance, de l'élaboration et/ou de la réplication du VIH chez des patients humains et à la prévention et au traitement du syndrome d'immunodéficience acquise (SIDA) et d'autres maladies induites par l'infection rétrovirale. Dans des aspects préférés, la présente invention concerne une méthode d'utilisation d'un nouveau type d'oligodésoxynucléotides, comprenant des unités de 4-thio-2'désoxyuridylate, destinés à la prévention et au traitement du virus de l'immunodéficience humaine type 1 (HIV) de type sauvage et chimio-résistant, l'agent pathogène qui cause le SIDA.
Aradi Janos
Bardos Thomas J.
Dunn Joseph A.
Cassan Maclean
Therex Technologies Inc.
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