Methods for inhibiting viral replication in vivo

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/50 (2006.01) A61K 45/06 (2006.01) A61K 47/48 (2006.01) A61P 31/14 (2006.01) A61P 35/00 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2506244

The present invention is directed to methods of modulating viral replication in vivo comprising administering to an individual a therapeutically or prophylactically effective amount of a composition comprising arginine deiminase modified with polyethylene glycol, to methods of concurrently modulating viral replication and treating cancer, and to methods of modulating nitric oxide levels in a patient, among others.

La présente invention se rapporte à des méthodes de modulation d'une réplication virale in vivo, qui consistent à administrer à un sujet une quantité efficace d'un point de vue thérapeutique ou prophylactique d'une composition comportant de l'arginine déiminase modifiée par du polyéthylène glycol. L'invention se rapporte également à des méthodes permettant simultanément de moduler une réplication virale et de traiter un cancer, ainsi qu'à des méthodes de modulation, entre autres, des taux de monoxyde d'azote chez un patient.

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