Methods for ligand discovery

Details Methods for ligand discovery Methods for ligand discovery

C - Chemistry, Metallurgy

12

Q

C12Q 1/00 (2006.01) C07D 207/46 (2006.01) C07D 333/38 (2006.01) C07D 333/70 (2006.01) C07D 401/04 (2006.01) C07D 405/12 (2006.01) C12Q 1/70 (2006.01) G01N 33/53 (2006.01) C07B 61/00 (2006.01)

Patent

CA 2464094

The present invention provides novel methods for ligand discovery. The inventive methods rely on a process termed "tethering" where potential ligands are covalently bonded or "tethered" to a target and subsequently identified as exemplified by the figure.

Nouveaux procédés de découverte de ligands qui reposent sur un processus nommé "amarrage" selon lesquels des ligands potentiels sont liés de manière covalente ou "amarrés" à une cible, puis identifiés.

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