Methods for making central nervous system agents that are...

C - Chemistry – Metallurgy – 07 – D

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C07D 231/56 (2006.01) C07D 231/54 (2006.01)

Patent

CA 2719018

The invention discloses compounds of formula ( II ): and methods of making the compounds, which are VR1 antagonists that are useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity.

Cette invention concerne des composés de formule (II) : et des procédés de préparation desdits composés, qui sont des antagonistes de VR1 utiles dans le traitement de la douleur, de l'hyperalgie thermique inflammatoire, de l'incontinence urinaire et de la suractivité de la vessie.

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