A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 49/00 (2006.01) A61K 49/22 (2006.01) B01J 13/02 (2006.01) B01J 13/04 (2006.01)
Patent
CA 2166459
Encapsulated gas microspheres having improved pressure resistance and stability are made by: mixing an aqueous solution of a filmogenic protein such as human serum albumin with a water insoluble gas such as perfluoropropane and subjecting the mixture to ultrasonic or mechanical cavitation in the absence of oxygen in an apparatus that is closed to the atmosphere.
On obtient des microsphères de gaz encapsulées, ayant une résistance à la pression et une stabilité améliorées, en mélangeant une solution aqueuse d'une protéine filmogène, telle que l'albumine du sérum humain, avec un gaz insoluble dans l'eau, tel que le perfluoropropane, et en soumettant le mélange à une cavitation ultrasonique ou mécanique en l'absence d'oxygène dans un appareil qui est fermé à l'atmosphère.
Hamilton Kenneth
Hulle Carl
Jablonski Edward G.
Lambert Karel J.
Lohrmann Rolf
Borden Ladner Gervais Llp
Molecular Biosystems Inc.
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