Methods for making optically active...

Details Methods for making optically active... Methods for making optically active...

C - Chemistry, Metallurgy

07

D

C07D 207/416 (2006.01) C07D 207/14 (2006.01)

Patent

CA 2337544

A method for making an optically active 3- aminopyrrolidine-2,5-dione derivative represented by the formula (3) includes cyclizing an optically active asparagine ester derivative represented by the formula (1) or (2), or an acid salt thereof. A method for making an optically active 3-aminopyrrolidine derivative represented by the formula (9) includes reducing the optically active 3- aminopyrrolidine-2,5-dione derivative represented by the formula (3). A method f'or making an optically active 3- aminopyrrolidine derivative includes hydrogenolyzing the optically active 3-aminopyrrolidine derivative represented by the formula (9).

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