Methods for manipulating the avian genome

Details Methods for manipulating the avian genome Methods for manipulating the avian genome

C - Chemistry, Metallurgy

12

N

C12N 15/00 (2006.01) A01K 67/027 (2006.01) C07K 14/62 (2006.01) C07K 16/02 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2375441

The invention features a method for introducing a nucleic acid molecule into the genome of an avian species by contacting in vivo a blastodermal cell of a fertilized egg with the nucleic acid molecule, which nucleic acid is not associated with a viral coat protein. The invention also encompasses transgenic avian animals and methods of producing such transgenic animals.

L'invention concerne un procédé servant à introduire une molécule d'acide nucléique dans le génome d'une espèce aviaire, ce qui consiste à mettre en contact in vivo une cellule blastodermique d'un oeuf fertilisé avec la molécule d'acide nucléique, cet acide nucléique n'étant pas associé à une protéine de coque virale. Elle concerne également des animaux aviaires transgéniques et des procédés permettant d'obtenir ces animaux transgéniques.

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