Methods for modulating neuronal cell death

Details Methods for modulating neuronal cell death Methods for modulating neuronal cell death

A - Human Necessities

61

K

A61K 31/185 (2006.01) A61K 31/66 (2006.01)

Patent

CA 2333203

The invention provides methods of inhibiting A.beta.-induced neuronal cell death. The invention further provides methods of providing neuroprotection to a subject and methods of treating a disease state characterized by A.beta.- induced neuronal cell death in a subject. Methods of inhibiting p75 receptor mediated neuronal cell death, as well as methods of treating a disease state in a subject characterized by p75 receptor mediated neuronal cell death are provided.

L'invention concerne des méthodes d'inhibition de mort de cellules neuronales induite par A.beta.. L'invention concerne en outre des méthodes permettant de fournir une neuroprotection à un sujet et des méthodes de traitement d'un état de maladie caractérisé par une mort de cellule neuronale induite par A.beta. chez un sujet. L'invention concerne aussi des méthodes d'inhibition d'une mort de cellule neuronale induite par un récepteur de p75, ainsi que des méthodes de traitement d'un état de maladie chez un sujet se caractérisant par une mort de cellules neuronales induite par un récepteur de p75.

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