Methods for modulating promoter responsible for beta amyloid...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/66 (2006.01) A61K 38/19 (2006.01) C07K 14/61 (2006.01) C12N 15/85 (2006.01) C12P 21/00 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2025960

31, 124 METHODS FOR MODULATING PROMOTER RESPONSIBLE FOR BETA AMYLOID PRECURSOR PROTEIN EXPRESSION ABSTRACT OF THE INVENTION The present invention relates to a method for controlling the expression of the beta amyloid precursor protein, a key protein involved in Alzheimer's Disease. Further, the present invention relates to a promoter reporter system useful in studying the effects agents have on the expression of the beta amyloid precursor protein and also provides a method for treating Alzheimer's Disease by regulating activities on the promoter system.

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