C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/55 (2006.01) C07C 31/18 (2006.01) C07D 303/04 (2006.01) C07D 303/18 (2006.01) C07D 303/38 (2006.01) C07D 307/20 (2006.01) C07K 16/40 (2006.01) C12N 1/19 (2006.01) C12N 9/14 (2006.01) C12N 15/81 (2006.01) C12P 21/02 (2006.01) C12P 41/00 (2006.01)
Patent
CA 2604928
The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific internal epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors. Also embraced by the invention are methods for obtaining optically active internal epoxides and corresponding optically active internal diols.
L'invention concerne des souches de levures, ainsi que des polypeptides codés par des gènes de ces souches de levures, qui ont une activité d'époxyde hydrolase interne énantiospécifique. L'invention concerne également des molécules d'acides nucléiques codant pour ces polypeptides, des vecteurs contenant ces molécules d'acides nucléiques, ainsi que des cellules contenant ces vecteurs. L'invention concerne en outre des procédés d'obtention d'époxydes internes optiquement actifs et de diols internes optiquement actifs correspondants.
Abrahams Nasreen
Botes Adriana Leonora
Labuschagne Michel
Lotter Jeanette
Mitra Robin Kumar
Csir
Gowling Lafleur Henderson Llp
Oxyrane Uk Limited
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