Methods for parallel detection of compositions having...

Details Methods for parallel detection of compositions having... Methods for parallel detection of compositions having...

G - Physics

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G01R 33/46 (2006.01) B01L 3/00 (2006.01) C12N 5/10 (2006.01) C12N 15/00 (2006.01) G01N 24/08 (2006.01) G01R 33/485 (2006.01) G01R 33/483 (2006.01)

Patent

CA 2396553

Methods and apparatuses for performing high throughput magnetic resonance imaging spectroscopy, e.g., to screen libraries of chemical or biological compositions for a compound of interest, are provided. Methods of identifying metabolic disorder genes, modulatory compounds and catalysts, and methods of optimizing reaction conditions, using high throughout MRI screening, are also provided.

L'invention concerne des procédés et appareils permettant d'exécuter une spectroscopie à haut rendement utilisant l'imagerie par résonance magnétique (IRM), par exemple pour analyser des bibliothèques de compositions chimiques ou biologiques d'un composé d'intérêt. L'invention concerne également des procédés d'identification de gènes de troubles métaboliques, de composés et catalyseurs modulateurs, ainsi que des procédés d'optimisation de conditions de réaction par criblage à haut rendement utilisant l'IRM.

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