Methods for positive immunoselection of stem cells

Details Methods for positive immunoselection of stem cells Methods for positive immunoselection of stem cells

Category

C - Chemistry, Metallurgy

Subcategory

12

Subsubcategory

N

IPC codes

C12N 5/00 (2006.01) A61K 35/14 (2006.01) A61K 35/28 (2006.01) C07K 16/28 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) A61K 35/12 (2006.01)

Type

Patent

Patent number

CA 2141428

Description

2141428 9402016 PCTABS00030 The invention relates to improved methods and kits for the positive immunoselection of target cells wherein the cells are immobilized to a solid matrix via an immune complex containing a soluble hapten and an anti-hapten antibody and are dissociable by hapten competition. The invention in particular relates to an improved positive immunoselection for purifying lympho-hematopoietic stem and progenitor cells from heterogeneous cell compositions, and a novel immune reagent for effecting this purification.

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