Methods for predicting and detecting intolerance to an...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C07H 21/04 (2006.01) G01N 33/92 (2006.01) C12N 9/20 (2006.01) C12N 15/11 (2006.01) C12N 15/55 (2006.01)

Patent

CA 2640415

The invention describes methods and tools for the identification of drug intolerance into subjects receiving an hypolipidemic agent. The invention further describes methods and tools for the prediction of drug intolerance in subjects in need of hypolipidemic agents. Some aspects of the invention are based on the assessment of the subject plasma glycerol concentrations. Some aspects of the invention are based on the assessment of the subject HDL-triglycerides concentration. Some other aspects are based on the identification of hepatic lipase gene variants in a subject genome.

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