Methods for preparation and use of...

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A - Human Necessities

61

K

A61K 31/592 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01)

Patent

CA 2517125

A method of inhibiting the hyperproliferation of malignant or neoplastic cells, comprising treating the cells with an antiproliferative amount of l.alpha.,24(S)-dihydroxyvitamin D2. The method also includes the co- administration of cyotoxic agents with the 1.alpha.,24(S)-dihydroxyvitamin D2.

L'invention concerne une méthode permettant d'inhiber l'hyperprolifération de cellules malignes ou néoplasiques, cette méthode consistant à traiter les cellules avec une quantité antiproliférative de 1.alpha.,24(S)-dihydroxyvitamine D¿2?. Ladite méthode consiste en outre à coadministrer des agents cytotoxiques avec la 1.alpha.,24(S)-dihydroxyvitamine D¿2?.

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