Methods for preparation of hb.sub.sag free gamma globulins...

Details Methods for preparation of hb.sub.sag free gamma globulins... Methods for preparation of hb.sub.sag free gamma globulins...

C - Chemistry, Metallurgy

07

K

167/139

C07K 16/06 (2006.01) A61K 39/29 (2006.01) B01D 15/08 (2006.01)

Patent

CA 1212625

METHODS FOR PREPARATION OF HBsAg FREE GAMMA GLOBULINS AND PRODUCTS Abstract Methods for producing from human serum, human gamma globu- lin essentially free of HBsAg and products resulting therefrom. Specifically provided are ion exchange resin/buffer systems capable of effectively removing HBsAg thought to be closely correlated with viral hepa- titis type B infectivity. Additional steps can include ultrafiltration to increase reduction of any virus not removed in the column passage as well as the addition of anti-HBg to substantially eliminate all infectivity.

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