Methods for preparing 1-deoxy paclitaxels

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 305/14 (2006.01) A61K 31/335 (2006.01) A61K 31/38 (2006.01) A61K 31/395 (2006.01) A61K 31/665 (2006.01) A61K 31/67 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 407/12 (2006.01) C07D 407/14 (2006.01) C07D 493/08 (2006.01) C07F 9/655 (2006.01) C07F 9/6558 (2006.01)

Patent

CA 2227020

The present invention provides methods for making a novel class of 1-deoxy paclitaxel derivatives. These derivatives include 1-deoxy paclitaxel. The derivatives of the present invention are potent cytotoxic agents.

L'invention porte sur des méthodes pour préparer une nouvelle classe de dérivés de 1-désoxypaclitaxel. Ces dérivés comprennent le 1-désoxypaclitaxel. Les dérivés de la présente invention sont de puissants agents cytotoxiques.

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